Left ventricular unloading during reperfusion.
نویسندگان
چکیده
منابع مشابه
Left ventricular unloading during reperfusion.
1543 it before publication.' We have recently become aware of a published thesis by Margot M. Bartelings8 at the University of Leiden that discusses cardiac development and uses the new terminology of Pexieder et a17 as well as the classic nomenclature. Although we are in general satisfied with this suggested nomenclature,7 we believe it would benefit from clarification on two points. For our o...
متن کاملLeft ventricular unloading during reperfusion does not limit myocardial infarct size.
To determine whether venting the left ventricle during coronary reperfusion limits myocardial infarct size, we studied paced (200 beats/min) Langendorff rabbit hearts, perfused with blood from a support rabbit. A left coronary artery was occluded for 60 minutes, followed by 2 hours of reperfusion. Four experimental conditions, as follows, were used: In group 1 (control), the hearts contracted i...
متن کاملLeft ventricular unloading before reperfusion reduces endothelin-1 release and calcium overload in porcine myocardial infarction.
OBJECTIVES The aim of this study was to test the hypothesis that after an acute myocardial infarction, endothelin-1 release with subsequent calcium overload is a mediator of myocardial reperfusion injury, which can be inhibited, in part, by left ventricular unloading immediately before reperfusion. We recently have reported that left ventricular unloading before reperfusion reduces infarct size...
متن کاملVentricular unloading, tissue angiotensin II, matrix modulation, and function during left ventricular assist device support.
eart failure (HF) has become the major epidemic of the ew millennium, and use of the left ventricular (LV) assist evice (LVAD) for mechanical support in end-stage HF is ncreasing. Introduced as an alternative to heart transplanation, LVADs were approved by the Food and Drug dministration a decade ago to provide a bridge to translantation in the moribund end-stage HF patient waiting or a donor h...
متن کاملMechanically unloading the left ventricle before coronary reperfusion reduces left ventricular wall stress and myocardial infarct size.
BACKGROUND Ischemia/reperfusion injury worsens infarct size, a major determinant of morbidity and mortality after acute myocardial infarction (MI). We tested the hypothesis that reducing left ventricular wall stress with a percutaneous left atrial-to-femoral artery centrifugal bypass system while delaying coronary reperfusion limits myocardial injury in a model of acute MI. METHODS AND RESULT...
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ژورنال
عنوان ژورنال: Circulation
سال: 1990
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.82.4.1543